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Recombinant CD86 抗体 (AA 24-245)

This anti-CD86 antibody is a 兔 单克隆 antibody detecting CD86 in FACS, WB, IP 和 ICC. Suitable for 小鼠.
产品编号 ABIN7795646
发货至: 中国

Quick Overview for Recombinant CD86 抗体 (AA 24-245) (ABIN7795646)

抗原

See all CD86 抗体
CD86

抗体类型

Recombinant Antibody

适用

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小鼠

宿主

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克隆类型

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  • 2
单克隆

标记

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This CD86 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

克隆位点

BLR255L
  • 抗原表位

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    AA 24-245

    原理

    Rabbit anti-CD86 Recombinant Monoclonal Antibody [BLR255L]

    纯化方法

    Purified

    免疫原

    Residues 24-245 (ECD)

    亚型

    IgG
  • 应用备注

    Flow-Cyt,Live or cells fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IP,6 μL/mg lysate ,WB,11000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1000 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2 - 8 °C

    有效期

    12 months
  • 抗原

    CD86

    别名

    CD86

    背景

    CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. CD86 is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response [taken from NCBI Entrez Gene (Gene ID: 942)].

    基因ID

    12524

    UniProt

    P42082

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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