TS (C-Term) 抗体
The 兔 多克隆 anti-TS antibody is suitable to detect TS in samples from 人 和 小鼠. It has been validated for WB, IHC 和 IP.
产品编号 ABIN7795593
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for TS (C-Term) 抗体 (ABIN7795593)
抗原
TS
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
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抗原表位
- C-Term
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原理
- Rabbit anti-TS Antibody Affinity Purified
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预测反应
- Bovine,Dog,Monkey,Pig,Rabbit,Rat
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纯化方法
- Antigen Affinity Purified
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免疫原
- Between 263 and C-terminus
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亚型
- IgG
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应用备注
- IHC,1500 - 12000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,6 μg/mg lysate,WB,12000 - 110,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- TS
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背景
- Thymidylate synthetase (TS) catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. TS is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs [taken from NCBI Entrez Gene (Gene ID: 7298)].
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基因ID
- 7298
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UniProt
- P04818
抗原
-
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