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Recombinant CD19 抗体

This anti-CD19 antibody is a 小鼠 单克隆 antibody detecting CD19 in ELISA, Func, Neut 和 IGA. Suitable for 人.
产品编号 ABIN7795325
发货至: 中国

Quick Overview for Recombinant CD19 抗体 (ABIN7795325)

抗原

See all CD19 抗体
CD19 (CD19 Molecule (CD19))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD19 antibody is un-conjugated

应用范围

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ELISA, Functional Studies (Func), Neutralization (Neut), Immunogenicity Assay (IGA)

质量等级

In vivo Grade

克隆位点

FMC63
  • Expression System

    Mammalian cells

    原理

    In vivo Grade Recombinant Anti-human CD19 Monoclonal Antibody (Clone: FMC63), Mouse IgG2a Kappa

    产品特性

    The FMC63 antibody binds to the human CD19 protein, a transmembrane protein expressed in all B lineage cells including human plasma cells. CD19 plays two major roles in human B cells: it acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane, and works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. CD19 is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.

    纯化方法

    Protein A or G affinity column

    纯度

    >95 % by reducing SDS-PAGE

    内毒素水平

    < 1 EU per 1 mg of the protein by the LAL method

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    > 3 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • 抗原

    CD19 (CD19 Molecule (CD19))

    别名

    CD19

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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