Recombinant SARS-CoV-2 Spike (Sotrovimab Biosimilar) 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant SARS-CoV-2 Spike (Sotrovimab Biosimilar) 抗体 (ABIN7795140)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
Expression System
- Mammalian cells
-
原理
- Afucosylated Sotrovimab Biosimilar, SARS-CoV-2 Spike Monoclonal Antibody
-
产品特性
- What is sotrovimab biosimilar research grade? Sotrovimab is an Fc-engineered human monoclonal antibody directed against the spike protein of SARS-CoV-2. sotrovimab is a human monoclonal antibody (IgG1κ isotype). sotrovimab biosimilar uses the same protein sequences as the therapeutic antibody sotrovimab. sotrovimab/imdevimab is a combination medicine used for the treatment and prevention of COVID-19. It consists of two human monoclonal antibodies, sotrovimab and imdevimab that must be mixed together and administered as an infusion or subcutaneous injection. The combination of two antibodies is intended to prevent mutational escape. sotrovimab and imdevimab bind distinct epitopes on the RBD with dissociation constants KD of 46 and 47 pM, respectively. Please contact us if you are interested in the anti-SARS-CoV-2 spike monoclonal antibody imdevimab biosimilar.
-
纯化方法
- Protein A or G affinity column
-
纯度
- >95 % by reducing SDS-PAGE
-
内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- > 3 mg/mL
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
-
-
- SARS-CoV-2 Spike (Sotrovimab Biosimilar)
-
别名
- Sotrovimab Biosimilar
-
物质类
- Biosimilar
抗原
-