Recombinant VEGFA (Brolucizumab Biosimilar) 抗体
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Quick Overview for Recombinant VEGFA (Brolucizumab Biosimilar) 抗体 (ABIN7795130)
抗原
抗体类型
适用
宿主
克隆类型
应用范围
质量等级
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Expression System
- Mammalian cells
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原理
- Brolucizumab Biosimilar, VEGF-A Monoclonal Antibody
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产品特性
- Brolucizumab Biosimilar uses the same protein sequences as the therapeutic antibody brolucizumab. Brolucizumab is a monoclonal antibody indicated to treat neovascular age related macular degeneration. Brolucizumab is a vascular endothelial growth factor (VEGF) inhibitor which targets the major VEGF-A isoforms: VEGF110, VEGF121, and VEGF165. Inhibition of these VEGF-A isoforms reduce proliferation of endothelial cells, vascularization of the tissue, and permeability of the vasculature.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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免疫原
- Human VEGF-A
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- VEGFA (Brolucizumab Biosimilar)
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别名
- Brolucizumab Biosimilar
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物质类
- Biosimilar
抗原
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