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Recombinant CD38 (Isatuximab Biosimilar) 抗体

The Humanized 单克隆 anti-CD38 (Isatuximab Biosimilar) antibody (ABIN7795129) specifically detects CD38 (Isatuximab Biosimilar) in FACS 和 in vivo. The antibody is reactive with 人 samples.
产品编号 ABIN7795129
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Recombinant CD38 (Isatuximab Biosimilar) 抗体 (ABIN7795129)

抗原

CD38 (Isatuximab Biosimilar)

抗体类型

Recombinant Antibody

适用

宿主

  • 2
  • 2
  • 1
  • 1
Humanized

克隆类型

  • 3
  • 2
单克隆

标记

  • 4
  • 1
This CD38 (Isatuximab Biosimilar) antibody is un-conjugated

应用范围

  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), In vivo Studies (in vivo)

质量等级

Research Grade
  • Expression System

    Mammalian cells

    原理

    Isatuximab Biosimilar, CD38 Monoclonal Antibody

    产品特性

    Isatuximab Biosimilar uses the same protein sequences as the therapeutic antibody isatuximab. Isatuximab is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line. Structurally, isatuximab is comprised of two identical immunoglobulin kappa light chains and two identical immunoglobulin gamma heavy chains. It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some immune cells that is highly expressed by malignant plasma cells in multiple myeloma. Along with daratumumab, another anti-CD38 monoclonal antibody, isatuximab constitutes a novel treatment modality for patients with difficult-to-treat multiple myeloma.

    纯化方法

    Protein A or G affinity column

    纯度

    >95 % by reducing SDS-PAGE

    内毒素水平

    < 1 EU per 1 mg of the protein by the LAL method

    免疫原

    Human CD38
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    > 3 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • 抗原

    CD38 (Isatuximab Biosimilar)

    别名

    Isatuximab Biosimilar

    物质类

    Biosimilar
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