Recombinant CD38 (Isatuximab Biosimilar) 抗体
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北京 101111
Quick Overview for Recombinant CD38 (Isatuximab Biosimilar) 抗体 (ABIN7795129)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
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Expression System
- Mammalian cells
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原理
- Isatuximab Biosimilar, CD38 Monoclonal Antibody
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产品特性
- Isatuximab Biosimilar uses the same protein sequences as the therapeutic antibody isatuximab. Isatuximab is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line. Structurally, isatuximab is comprised of two identical immunoglobulin kappa light chains and two identical immunoglobulin gamma heavy chains. It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some immune cells that is highly expressed by malignant plasma cells in multiple myeloma. Along with daratumumab, another anti-CD38 monoclonal antibody, isatuximab constitutes a novel treatment modality for patients with difficult-to-treat multiple myeloma.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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免疫原
- Human CD38
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD38 (Isatuximab Biosimilar)
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别名
- Isatuximab Biosimilar
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物质类
- Biosimilar
抗原
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