Recombinant CD3E (Muromonab Biosimilar) 抗体
This anti-CD3E (Muromonab Biosimilar) antibody is a 小鼠 单克隆 antibody detecting CD3E (Muromonab Biosimilar) in FACS 和 in vivo. Suitable for 人.
Quick Overview for Recombinant CD3E (Muromonab Biosimilar) 抗体 (ABIN7795115)
抗原
CD3E (Muromonab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This CD3E (Muromonab Biosimilar) antibody is un-conjugated
应用范围
Flow Cytometry (FACS), In vivo Studies (in vivo)
质量等级
Research Grade
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Expression System
- Mammalian cells
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原理
- Muromonab Biosimilar, CD3 Monoclonal Antibody
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产品特性
- Muromonab Biosimilar uses the same protein sequences as the therapeutic antibody muromonab (OKT3). Muromonab (OKT-3) is a monoclonal anti-CD3 antibody used as immunosuppressive therapy in kidney, heart, and liver transplant patients. Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93 % monomeric immune globulin G type 2a (IgG2a). Muromonab binds to the T-cell surface glycoprotein CD3 epsilon chain. It appears to kill CD-3 positive cells by inducing Fc mediated apoptosis, antibody mediated cytotoxicity and complement-dependent cytotoxicity.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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免疫原
- Human CD3
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anti-CD3E (Muromonab Biosimilar) antibody
适用: 人 FACS 宿主: 兔 Chimeric OKT-3 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD3E (Muromonab Biosimilar)
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别名
- Muromonab Biosimilar
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物质类
- Biosimilar
抗原
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