Recombinant CD79B (Polatuzumab Biosimilar) 抗体
This anti-CD79B (Polatuzumab Biosimilar) antibody is a Humanized 单克隆 antibody detecting CD79B (Polatuzumab Biosimilar) in FACS 和 in vivo. Suitable for 人.
Quick Overview for Recombinant CD79B (Polatuzumab Biosimilar) 抗体 (ABIN7795113)
抗原
CD79B (Polatuzumab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
Humanized
克隆类型
单克隆
标记
This CD79B (Polatuzumab Biosimilar) antibody is un-conjugated
应用范围
Flow Cytometry (FACS), In vivo Studies (in vivo)
质量等级
Research Grade
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Expression System
- Mammalian cells
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原理
- Polatuzumab Biosimilar, Human CD79B Monoclonal Antibody
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产品特性
- What is polatuzumab biosimilar research grade? Polatuzumab is a humanized IgG1-kappa monoclonal antibody against the human CD79B protein, which is ubiquitously expressed on the surface of malignant B cells. Polatuzumab vedotin is used to treat diffuse large B-cell lymphoma (DLBCL) after at least two other cancer treatments did not work or have stopped working. It is given in combination with bendamustine (Bendeka, Treanda) and a medicine that contains rituximab (Rituxan). Polatuzumab vedotin works by attaching to CD79b and releasing a toxic substance that kills the cancer cells. Polatuzumab biosimilar uses the same protein sequences as the therapeutic antibody polatuzumab.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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免疫原
- Human CD79B
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anti-CD79B (Polatuzumab Biosimilar) antibody
Research Grade 适用: 人 FACS, ELISA 宿主: Humanized Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD79B (Polatuzumab Biosimilar)
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别名
- Polatuzumab Biosimilar
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物质类
- Biosimilar
抗原
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