Recombinant CD80 (Galiximab Biosimilar) 抗体
This anti-CD80 (Galiximab Biosimilar) antibody is a Humanized 单克隆 antibody detecting CD80 (Galiximab Biosimilar) in FACS 和 in vivo. Suitable for 人.
Quick Overview for Recombinant CD80 (Galiximab Biosimilar) 抗体 (ABIN7795110)
抗原
CD80 (Galiximab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
Humanized
克隆类型
单克隆
标记
This CD80 (Galiximab Biosimilar) antibody is un-conjugated
应用范围
Flow Cytometry (FACS), In vivo Studies (in vivo)
质量等级
Research Grade
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Expression System
- Mammalian cells
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原理
- Galiximab Biosimilar, CD80 Monoclonal Antibody
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产品特性
- A humanized IgG1 monoclonal antibody directed against CD80, the natural ligand for the T-cell antigen CD28 which mediates T-cell and B-cell adhesion. Galiximab binds to CD80 expressed on the cell surfaces of follicular lymphomas, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC). CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes and is often expressed at low levels on the surfaces of follicular lymphoma cells and other lymphoid malignancies. Galiximab, an IgG(1) anti-CD80 antibody, binds to CD80, a costimulatory molecule involved in T-cell activation. Reduction in lesional, activated T cells induces improvement in psoriatic plaques.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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免疫原
- Human CD80
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anti-CD80 (Galiximab Biosimilar) antibody
适用: 人 FACS, BR, ELISA, IHC, IP, WB 宿主: 兔 Chimeric IDEC-114 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD80 (Galiximab Biosimilar)
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别名
- Galiximab Biosimilar
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物质类
- Biosimilar
抗原
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