Recombinant MS4A1 (Rituximab Biosimilar) 抗体
This anti-MS4A1 (Rituximab Biosimilar) antibody is a 小鼠 单克隆 antibody detecting MS4A1 (Rituximab Biosimilar) in FACS 和 in vivo. Suitable for 人.
Quick Overview for Recombinant MS4A1 (Rituximab Biosimilar) 抗体 (ABIN7795085)
抗原
MS4A1 (Rituximab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This MS4A1 (Rituximab Biosimilar) antibody is un-conjugated
应用范围
Flow Cytometry (FACS), In vivo Studies (in vivo)
质量等级
Research Grade
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Expression System
- Mammalian cells
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原理
- Rituximab Biosimilar, Endotoxin 0.05 EU/mg
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产品特性
- B-lymphocyte antigen CD20 encoded by the MS4A1 gene is an activated-glycosylated phosphoprotein on the surface of all B-cells. The function of the membrane protein is to stimulate B-cell immune response, specifically against T-independent antigens though its natural ligand remains unknown. CD20 is important for the development and differentiation of B-cells into plasma cells. CD20 belongs to the membrane-spanning 4A family with common structural features, similar intron/exon splice boundaries, and unique expression patterns among hematopoietic cells and nonlymphoid tissues. Rituximab, a chimeric anti-CD20 monoclonal antibody, destroys B cells and is used to treat diseases with excessive numbers of B cells, overactive B cells, or dysfunctional B cells, such as many lymphomas, leukemias, transplant rejection, and autoimmune disorders.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- Less than 0.5 EU/mg of protein as determined by LAL method
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免疫原
- Human lymphoblastoid cell line SB
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anti-MS4A1 (Rituximab Biosimilar) antibody
适用: 人, Cynomolgus, 猕猴 FACS 宿主: 兔 Chimeric 10F381 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- MS4A1 (Rituximab Biosimilar)
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别名
- Rituximab Biosimilar
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物质类
- Biosimilar
抗原
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