Recombinant Belatacept Biosimilar 抗体
The 小鼠 单克隆 anti-Belatacept Biosimilar antibody (ABIN7795081) specifically detects Belatacept Biosimilar in FACS 和 in vivo.
The antibody is reactive with 人 samples.
产品编号 ABIN7795081
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Recombinant Belatacept Biosimilar 抗体 (ABIN7795081)
抗原
Belatacept Biosimilar
抗体类型
Recombinant Antibody
适用
人
宿主
小鼠
克隆类型
单克隆
应用范围
Flow Cytometry (FACS), In vivo Studies (in vivo)
质量等级
Research Grade
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Expression System
- Mammalian cells
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原理
- Belatacept Biosimilar
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产品特性
- Belatacept (trade name Nulojix, Bristol-Myers-Squibb), a fusion protein of a Fc fragment (human IgG1 isotype) and the extracellular domain of CTLA-4, can be used to extend graft survival while limiting the toxicity generated by standard immune suppressing regimens, such as calcineurin inhibitors. Belatacept differs from abatacept (trade name Orencia) by only 2 amino acids. The CTLA-4 protein is important for T-cell costimulation and selectively blocks the process of T-cell activation.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- Belatacept Biosimilar
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物质类
- Biosimilar
抗原
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