RSV 抗体
Our Local Distributor
北京 101111
Quick Overview for RSV 抗体 (ABIN7795022)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Anti-Respiratory Syncytial Virus (RSV)
-
特异性
- Respiratory Syncytial Virus (Clone RSV-210915) is specific for the fusion protein of RSV Types A&B. Background Respiratory syncytial virus (RSV) is a common respiratory virus that infects the majority of children by two years old1, 2. While usually mild, RSV can be serious in infants and older adults and is the leading cause of bronchiolitis and pneumonia in children less than one year of age in the United States1. A related pneumovirus, human metapneumovirus (hMPV), also significantly contributes to hospitalizations resulting from lower respiratory tract infection2. Antibodies have been described that bind and neutralize both RSV and hMPV fusion (F) proteins. RSV F protein is a type I integral membrane protein that is synthesized as a 574 amino acid inactive precursor, assembled into a trimer, post-translationally modified, then cleaved to produce F1, F2, and intervening peptide pep273. Functional F protein has both pre- and post-fusion conformations. RSV F protein is highly conserved among RSV isolates from both A and B subgroups3 and is the primary target for antiviral drug development3 with several antigenic regions capable of introducing neutralizing antibodies2. RSV and hMPV F protein share ~36 % sequence similarity.
-
交叉反应 （详细）
- This clone is non-reactive with: Influenza A & B, Adenovirus, Para 1-3, Measles, Mumps
-
纯化方法
- This monoclonal antibody is purified from ascites fluid or culture medium by protein A chromatography or sequential differential precipitations.
-
纯度
- >90 % monomer by analytical SEC and SDS-Page
-
-
anti-Respiratory Syncytial Virus (RSV) (AA 151-250) antibody
RSV 适用: 人, Human respiratory syncytial virus A, Virus IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Respiratory Syncytial Virus (RSV) antibodyRSV 适用: Respiratory Syncytial Virus (RSV) ELISA, IF, WB, Neut, IHC 宿主: 兔 Polyclonal unconjugated
-
-
限制
- 仅限研究用
-
-
-
浓度
- 1 μg/mL
-
缓冲液
- This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1 % sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- This product contains no stabilizing proteins and should be stored at 2-8°C until ready to use.
-
-
- RSV (Respiratory Syncytial Virus (RSV))
-
别名
- Respiratory Syncytial Virus
-
物质类
- Virus
抗原
-
