Influenza Virus Nucleoprotein 抗体 (Influenza A Virus)
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Quick Overview for Influenza Virus Nucleoprotein 抗体 (Influenza A Virus) (ABIN7795018)
抗原
See all Influenza Virus Nucleoprotein (IV NP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Influenza A, Nucleocapsid
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特异性
- Anti-Influenza A, Nucleoprotein (Clone IA-902) is specific for the Influenza A nucleocapsid. Background There are four types of Influenza (flu) viruses type A, B, C, and D. Influenza A and B viruses are routinely spread in people and other mammals, while also known for seasonal flu epidemics each year. Influenza A is the genus Alphainfluenzavirus of the virus family Orthomyxoviridae. Influenza A is classified into two main protein subtypes, hemagglutinin (HA) and neuraminidase (NA), located on the surface of the virus. Breaking down the proteins further, there are 18 hemagglutinin subtypes and 11 different neuraminidase subtypes1. Influenza A can be even further classified into specific clades (also known as groups) and sub-clades (also known as sub-groups) based on similarity of their HA/NA gene sequences1. The Nucleocapsid protein or nucleoprotein (NP) of the influenza virus A negative-strand RNA?s primary function is to encapsulate the virus genome for the purpose of RNA transcription, replication and packaging2. Specifically, NP is the most abundant viral protein in infected cells2, therefore the NP can be and has been used for anti-influenza drug development3. The NP of influenza A and B viruses share up to 38 % of their amino acid sequence, indicating region functionality differences at the amino acid level4.
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纯化方法
- This monoclonal antibody is purified from ascites fluid or culture medium by protein A chromatography or sequential differential precipitations.
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纯度
- >90 % monomer by analytical SEC and SDS-Page
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亚型
- IgG1
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anti-Influenza Virus Nucleoprotein antibody (Influenza A Virus H2N2) (H1N1), (H2N2), (H3N2), (H5N1), (H5N2)
IV NP 适用: Influenza A Virus H2N2 ELISA, WB, IF, IHC, IP, IC 宿主: 小鼠 Monoclonal C43 unconjugated
anti-Influenza Virus Nucleoprotein antibody (Influenza A Virus H2N2) (H1N1), (H2N2), (H3N2), (H5N1), (H5N2) (HRP)IV NP 适用: Influenza A Virus H2N2 ELISA, WB, IHC, IC 宿主: 小鼠 Monoclonal C43 HRP
anti-Influenza Virus Nucleoprotein antibody (Influenza B Virus (B/Lee/40))IV NP 适用: Influenza B Virus ELISA 宿主: 小鼠 Monoclonal 1A2A11 unconjugated
anti-Influenza Virus Nucleoprotein antibody (Influenza A Virus H2N2) (AA 2-498)IV NP 适用: Influenza A Virus H2N2 ELISA 宿主: 小鼠 Monoclonal 9C11 unconjugated
anti-Influenza Virus Nucleoprotein antibody (Influenza A Virus) (AA 428-441)IV NP 适用: Influenza A Virus ELISA, ICC, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Influenza Virus Nucleoprotein antibody (Influenza A Virus) (AA 58-77)IV NP 适用: Influenza A Virus WB 宿主: 兔 Polyclonal unconjugated
anti-Influenza Virus Nucleoprotein antibody (Influenza B Virus)IV NP 适用: Influenza B Virus ELISA, WB, PrA 宿主: 小鼠 Monoclonal B267M unconjugated
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应用备注
- ELISA Recommended starting range 1:20-1:200 IF Recommended starting range 1:10-1:50
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限制
- 仅限研究用
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浓度
- 1 μg/mL
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缓冲液
- This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1 % sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- This product contains no stabilizing proteins and should be stored at 2-8°C until ready to use.
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- Influenza Virus Nucleoprotein (IV NP)
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别名
- Influenza A Nucleocapsid
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物质类
- Influenza Protein
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背景
- Common flu NP, Influenza A virus NP, NP, Nucleocapsid protein, Nucleoprotein, Protein N, Seasonal Influenza A (H1N1) Nucleocapsid Protein,
抗原
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