WNV E 抗体 (C-Term)
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Quick Overview for WNV E 抗体 (C-Term) (ABIN7794881)
抗原
See all WNV E 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-West Nile Virus Envelope Protein (CT) (WNV Env)
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特异性
- Rabbit Anti-West Nile Virus Envelope Protein (WNV Env) recognizes an epitope near the C-terminus of WNV Env. This polyclonal antibody was purified using affinity chromatography. Background West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state (reviewed in 1). Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins.1 While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway,2 the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein.3 The WNV receptor has recently been identified as alpha v beta 3 integrin.4
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限制
- 仅限研究用
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浓度
- 0.2 μg/mL
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缓冲液
- This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02 % sodium azide as a preservative.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
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- WNV E (West Nile Virus Envelope (WNV E))
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别名
- West Nile Virus Envelope Protein
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物质类
- Viral Protein
抗原
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