EBOV VP40 抗体
This anti-EBOV VP40 antibody is a 小鼠 单克隆 antibody detecting EBOV VP40 in ELISA, WB 和 BP. Suitable for Ebola Virus.
Quick Overview for EBOV VP40 抗体 (ABIN7794821)
抗原
EBOV VP40
(Ebola Virus Matrix protein VP40 (EBOV VP40))
适用
Ebola Virus
宿主
小鼠
克隆类型
单克隆
标记
This EBOV VP40 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Blocking Peptide (BP)
克隆位点
EB-977
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原理
- Anti-Ebola Virus, VP40 (EB-977)
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特异性
- Anti-Ebola Virus (Clone EB-977) has known reactivity for the viral antigen VP40 of Sudan and Zaire strains (reacts with VLPs). Background Ebola virus is a highly infectious and deadly enveloped RNA virus that belongs to the Filoviridae family. It causes severe and often fatal hemorrhagic fever in humans and non-human primates. Ebola is considered endemic in certain parts of Africa where outbreaks have occurred in various countries such as the Democratic Republic of Congo, Sudan, Guinea, Libera, Sierra Leone, and Uganda. VP40 is a matrix protein of Ebola virus that is the most abundantly expressed viral protein during infection. The protein plays an important role in viral assembly and budding with exogenous expression of VP40 being sufficient to induce the formation of viral-like particles. VP40 can oligomerize and the different oligomeric states have distinct functions during infection the octameric confirmation plays a critical role in regulating viral transcription while hexamers localize to the plasma membrane. Because of its critical role in the viral life cycle and abundance, VP40 has been used in diagnostic testing as well as potential therapeutics.
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纯化方法
- This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.
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纯度
- ≥90 %
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亚型
- IgG2b
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应用备注
- ELISA: 1:20 - 1:200,WB
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限制
- 仅限研究用
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浓度
- 1 μg/mL
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缓冲液
- Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1 % sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- This purified antibody is stable when stored at 2-8°C. Do not freeze.
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- EBOV VP40 (Ebola Virus Matrix protein VP40 (EBOV VP40))
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别名
- Ebola Virus, VP40
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物质类
- Viral Protein
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背景
- EB,
抗原
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