Ketamine 抗体
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北京 101111
Quick Overview for Ketamine 抗体 (ABIN7794724)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Ketamine-(Clone KET-1153)
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特异性
- Anti-Ketamine (clone KET-1153) is specific for ketamine. Ketamine - 100 % Norketamine - 60 % Background Ketamine is a nonbarbiturate dissociative anesthetic that has been approved for use in general anesthesia both alone and in combination with other medications. Ketamine's primary mechanism of action involves antagonizing N-methyl-D-aspartate (NMDA) receptors in the brain, leading to dissociation of sensory perceptions and producing analgesic and hallucinogenic effects. Recent research has shown long-lasting antidepressant activity and chronic pain relief likely due to structural brain changes induced by the drug. Ketamine has emerged as a novel and promising treatment for certain psychiatric conditions, such as treatment-resistant depression and post-traumatic stress disorder (PTSD), administered in controlled clinical settings. However, its misuse, particularly in recreational settings, raises concerns due to its dissociative effects and potential for addiction.
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纯化方法
- This monoclonal antibody is purified by ion exchange chromatography.
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纯度
- >90 % for SDS PAGE
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亚型
- IgG2a kappa
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限制
- 仅限研究用
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浓度
- 1 μg/mL
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缓冲液
- Formulated in 0.015M potassium phosphate buffered saline (0.85 % ), pH 7.2 and contains 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- This purified antibody is stable when stored at 2-8°C. Do not freeze.
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- Ketamine
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物质类
- Chemical
抗原
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