Anti-Ketamine (clone KET-1153) is specific for ketamine. Ketamine - 100 % Norketamine - 60 % Background Ketamine is a nonbarbiturate dissociative anesthetic that has been approved for use in general anesthesia both alone and in combination with other medications. Ketamine's primary mechanism of action involves antagonizing N-methyl-D-aspartate (NMDA) receptors in the brain, leading to dissociation of sensory perceptions and producing analgesic and hallucinogenic effects. Recent research has shown long-lasting antidepressant activity and chronic pain relief likely due to structural brain changes induced by the drug. Ketamine has emerged as a novel and promising treatment for certain psychiatric conditions, such as treatment-resistant depression and post-traumatic stress disorder (PTSD), administered in controlled clinical settings. However, its misuse, particularly in recreational settings, raises concerns due to its dissociative effects and potential for addiction.
纯化方法
This monoclonal antibody is purified by ion exchange chromatography.