Lipoarabinomannan (LAM) 抗体
This 兔 单克隆 antibody specifically detects Lipoarabinomannan in ELISA 和 IF. It exhibits reactivity toward Mycobacteria.
产品编号 ABIN7794695
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Lipoarabinomannan (LAM) 抗体 (ABIN7794695)
抗原
Lipoarabinomannan (LAM)
适用
Mycobacteria
宿主
兔
克隆类型
单克隆
标记
非结合性
应用范围
ELISA, Immunofluorescence (IF)
克隆位点
MYCO-8061
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原理
- Anti-Mycobacteria, LAM (MYCO-8061)
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特异性
- Anti-Mycobacteria (Clone MYCO-8061) is specific for the lipoarabinomannan of several Mycobacteria species including Mycobacterium tuberculosis (6 strains), M. bovis, M. smegmatis, M. leprae, M. avium, M. phlei, & M. parafortuitum. Background Mycobacterium is a diverse genus of bacteria that includes several pathogenic species responsible for causing diseases in humans, most notably Mycobacterium tuberculosis, the causative agent of tuberculosis (TB). Mycobacteria are characterized by their unique cell wall structure, which contains high levels of mycolic acids, making them resistant to many conventional antibiotics. In addition to M. tuberculosis, other medically important species include Mycobacterium leprae, responsible for leprosy, and Mycobacterium avium complex (MAC), causing opportunistic infections in immunocompromised individuals. Mycobacterium cell walls also contain a glycolipid known as Lipoarabinomannan (LAM), which plays a significant role in pathogenesis. LAM helps the bacteria evade the host immune system and modulate the host's inflammatory response. Additionally, LAM has been used as a diagnostic marker for TB infection, as it can be detected in patient samples such as sputum and urine. Understanding the unique characteristics of Mycobacterium and the role of molecules like LAM is crucial for the development of effective diagnostic tools and therapeutic strategies to combat mycobacterial infections.
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纯化方法
- This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.
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纯度
- >=90 %
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亚型
- IgG
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应用备注
- ELISA: 1:20-1:200,IF: 1:10-1:50
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限制
- 仅限研究用
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浓度
- 1 μg/mL
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缓冲液
- Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1 % sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- This purified antibody is stable when stored at 2-8°C. Do not freeze.
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- Lipoarabinomannan (LAM)
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别名
- LAM
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背景
- LAM, lipoarabinomannan, Mtb, TB, Tuberculosis,
抗原
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