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CD86 抗体 (AA 140-175)

Name: CD86 抗体 (AA 140-175)
SKU: ABIN736701
Availability: OutOfStock

This anti-CD86 antibody is a 兔多克隆 antibody detecting CD86 in FACS, WB, ELISA, IHC (fro), ICC, IHC (p), IF (cc) 和 IF (p). Suitable for 人, 小鼠, 大鼠和犬. This Primary Antibody has been cited in 13+ publications.

HeLa cell lysates probed with Rabbit Anti-CD86 Polyclonal Antibody, Unconjugated at 1:500 for 90 min at 37˚C. (CD86 抗体 (AA 140-175))

Formalin-fixed and paraffin embedded rat lung labeled with Anti-CD86/B7-2 Polyclonal Antibody, Unconjugated (ABIN736701) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (CD86 抗体 (AA 140-175))

IHC

L1 rat brain lysates L2 rat heart lysates probed with Anti CD86/B7-2 Polyclonal Antibody, Unconjugated (ABIN736701) at 1:200 overnight at 4 °C. (CD86 抗体 (AA 140-175))

SDS

Formalin-fixed and paraffin embedded human esophageal carcinoma tissue labeled with Anti-CD86/B7-2 Polyclonal Antibody , Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (CD86 抗体 (AA 140-175))

IHC (p)

Chronic phase glibenclamide reduces inflammation and improves the macrophage phenotype in EAE. (CD86 抗体 (AA 140-175))

IHC (p)

5 images

(13 references)

产品编号 ABIN736701

发货至: 中国

Datasheet as PDF

Quick Overview for CD86 抗体 (AA 140-175) (ABIN736701)

抗原

See all CD86 抗体

CD86

适用

人, 小鼠, 大鼠, 犬

宿主

兔

克隆类型

多克隆

标记

This CD86 antibody is un-conjugated

应用范围

Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

抗原表位
15

9

5

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4

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2

2

2

2

2

1

1

1

1

1

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1

1

1

1

1
AA 140-175

交叉反应

犬, 人, 小鼠, 大鼠

预测反应

Cow,Sheep,Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from rat CD86

亚型

IgG
anti-CD86 (CD86) (AA 37-272) antibody
CD86 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD86 (CD86) antibody
CD86 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, IF, ELISA, BP, StM, Coat 宿主: 兔 Monoclonal C86-2160R unconjugated Recombinant Antibody

anti-CD86 (CD86) antibody
CD86 适用: 人, 小鼠, 大鼠 FACS, IHC, IF, Func, BP, StM 宿主: 小鼠 Monoclonal BU63 unconjugated

anti-CD86 (CD86) antibody
CD86 适用: 人 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal BU63 unconjugated

anti-CD86 (CD86) antibody (FITC)
CD86 适用: 人 FACS 宿主: 小鼠 Monoclonal BU63 FITC

anti-CD86 (CD86) (AA 30-247) antibody
CD86 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-CD86 (CD86) antibody
CD86 适用: 人, 小鼠, 大鼠 FACS, IHC, IF, BP, StM 宿主: 小鼠 Monoclonal rC86-1146 unconjugated Recombinant Antibody

anti-CD86 (CD86) antibody
CD86 适用: 人, 小鼠, 大鼠 WB, IHC, IF, BP, StM 宿主: 小鼠 Monoclonal C86-1146 unconjugated

anti-CD86 (CD86) antibody
CD86 适用: 人 FACS, WB, IP, IHC (fro), Func 宿主: 小鼠 Monoclonal BU63 unconjugated

anti-CD86 (CD86) antibody (FITC)
CD86 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal GL-1 FITC

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Diehl, Kirchhoff, Hansmann: "CD86 is linked to apoptosis in canine histiocytic sarcoma." in: Frontiers in veterinary science, Vol. 12, pp. 1546047, (2025) (PubMed).

Lee, Yu, Trimpert, Benthani, Mairhofer, Richter-Pechanska, Wyler, Belenki, Kaltenbrunner, Pammer, Kausche, Firsching, Dietert, Schotsaert, Martínez-Romero, Singh, Kunz, Niemeyer, Ghanem, Salzer, Paar et al.: "Virus-induced senescence is a driver and therapeutic target in COVID-19. ..." in: Nature, Vol. 599, Issue 7884, pp. 283-289, (2021) (PubMed).

Han, Wang, Qin, Xia, Wu: "LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 83, (2018) (PubMed).

Chen, Zhang, Wang, Chen, Yan, Zhang, Zhang: "Peptide-modified chitosan hydrogels promote skin wound healing by enhancing wound angiogenesis and inhibiting inflammation." in: American journal of translational research, Vol. 9, Issue 5, pp. 2352-2362, (2017) (PubMed).

Zhang, Zhang, Yin, Li, Bao, Chen: "Variation and significance of secretory immunoglobulin A, interleukin 6 and dendritic cells in oral cancer." in: Oncology letters, Vol. 13, Issue 4, pp. 2297-2303, (2017) (PubMed).

Gerzanich, Makar, Guda, Kwon, Stokum, Woo, Ivanova, Ivanov, Mehta, Morris, Bryan, Bever, Simard: "Salutary effects of glibenclamide during the chronic phase of murine experimental autoimmune encephalomyelitis." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 177, (2017) (PubMed).

Xie, Wu, Zhou, Yang, Tian, Huang, Meng, Li: "PICK1 confers anti-inflammatory effects in acute liver injury via suppressing M1 macrophage polarization." in: Biochimie, Vol. 127, pp. 121-32, (2016) (PubMed).

Das, Singh, Majid, Sherman, Mukhopadhyay, Wright, Martin, Dunn, Baker: "Syndesome Therapeutics for Enhancing Diabetic Wound Healing." in: Advanced healthcare materials, Vol. 5, Issue 17, pp. 2248-60, (2016) (PubMed).

Chen, Li, Zhao, Liang, Ma, Li, Zhu: "Prevention of ultraviolet radiation‑induced immunosuppression by sunscreen in Candida albicans‑induced delayed‑type hypersensitivity." in: Molecular medicine reports, Vol. 14, Issue 1, pp. 202-8, (2016) (PubMed).

Ju, Xing, Yang, Zheng, Jia, Zhang, Ren: "An effective cytokine adjuvant vaccine induces autologous T-cell response against colon cancer in an animal model." in: BMC immunology, Vol. 17, Issue 1, pp. 31, (2016) (PubMed).

Chen, Shi, Zhang, Chen, Wang, Zhang, Tian, Yan, Li, Zhong, Xing, Zhang, Zhang: "Mesenchymal stem cell-laden anti-inflammatory hydrogel enhances diabetic wound healing." in: Scientific reports, Vol. 5, pp. 18104, (2016) (PubMed).

Evans, Jonason, Bussler, Torno, Veeraraghavan, Reilly, Doherty, Seils, Winter, Mallow, Kirk, Howell, Giralico, Scrivens, Klimatcheva, Fisher, Bowers, Paris, Smith, Zauderer: "Antibody blockade of semaphorin 4D promotes immune infiltration into tumor and enhances response to other immunomodulatory therapies." in: Cancer immunology research, (2015) (PubMed).

Gao, Zhang, Ding, Chen, Hu, Jiang, Li, Chen, Wang, Ye, Zhu: "Common expression of stemness molecular markers and early cardiac transcription factors in human Wharton's jelly-derived mesenchymal stem cells and embryonic stem cells." in: Cell transplantation, Vol. 22, Issue 10, pp. 1883-900, (2014) (PubMed).
抗原

CD86

别名

CD86

背景

Synonyms: B7-2, Cd86 antigen, Cd86, Membrane glycoprotein
Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

基因ID

56822

UniProt

O35531

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation