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SOCS2 抗体 (AA 1-100)

Cited in 3+ publications. This anti-SOCS2 antibody is a 兔 多克隆 antibody detecting SOCS2 in WB, ELISA, IF (cc), IF (p), IHC (fro) 和 IHC (p). Suitable for 大鼠.
产品编号 ABIN736028
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SOCS2 抗体 (AA 1-100) (ABIN736028)

抗原

See all SOCS2 抗体
SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

适用

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大鼠

宿主

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克隆类型

  • 34
  • 22
多克隆

标记

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This SOCS2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
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    AA 1-100

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Socs 2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Shin, Riew, Park, Pak, Lee: "Expression of SOCS2 mRNA and protein in the ischemic core and penumbra after transient focal cerebral ischemia in rats." in: Cell and tissue research, Vol. 364, Issue 1, pp. 67-81, (2016) (PubMed).

    Letellier, Schmitz, Baig, Beaume, Schwartz, Frasquilho, Antunes, Marcon, Nazarov, Vallar, Even, Haan: "Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer." in: British journal of cancer, Vol. 111, Issue 4, pp. 726-35, (2014) (PubMed).

    Zhu, Dai, Han, He, Mo, Chen, Chen, Wu, Yang, Jiang, Chen, Sun, Zhong: "Expression of SOCSs in human prostate cancer and their association in prognosis." in: Molecular and cellular biochemistry, Vol. 381, Issue 1-2, pp. 51-9, (2013) (PubMed).

  • 抗原

    SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

    别名

    Socs 2

    背景

    Synonyms: CIS2, SSI2, Cish2, SSI-2, SOCS-2, STATI2, Suppressor of cytokine signaling 2, Cytokine-inducible SH2 protein 2, CIS-2, STAT-induced STAT inhibitor 2, SOCS2

    Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

    基因ID

    8835

    UniProt

    O14508

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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