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DUSP4 抗体 (AA 301-394) (Cy5)

This Cy5-conjugated 兔 多克隆 anti-DUSP4 antibody specifically detects DUSP4 in WB, FACS, IF (cc) 和 IF (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN735387
发货至: 中国
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Quick Overview for DUSP4 抗体 (AA 301-394) (Cy5) (ABIN735387)

抗原

See all DUSP4 抗体
DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

适用

  • 57
  • 40
  • 10
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 54
  • 4

克隆类型

  • 54
  • 4
多克隆

标记

  • 26
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DUSP4 antibody is conjugated to Cy5

应用范围

  • 44
  • 25
  • 21
  • 13
  • 12
  • 12
  • 9
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 8
    • 6
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-394

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MKP-2

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

    别名

    Mkp-2/Dusp4

    背景

    Synonyms: Mitogen activated protein kinase phosphatase 2, Dual specicity phosphatase 4, Dual specicity protein phosphatase 4, Dual specicity protein phosphatase hVH2, DUSP 4, HVH 2, HVH2, MAP kinase phosphatase 2, Mitogen activated protein kinase phosphatase 2, MKP 2, MKP2, Serine/threonine specic protein phosphatase, TYP, VH 2, VH1 homologous phosphatase 2, VH2.

    Background: DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.

    基因ID

    1846

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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