Glutamate Receptor 3 抗体 (AA 451-550)
Quick Overview for Glutamate Receptor 3 抗体 (AA 451-550) (ABIN734603)
抗原
See all Glutamate Receptor 3 (GRIA3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 451-550
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GLUR3
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))
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别名
- GLUR3/GRIA 3
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背景
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Synonyms: GLUR3, GLURC, GluA3, MRX94, GLUR-C, GLUR-K3, Glutamate receptor 3, GluR-3, AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, GRIA3
Background: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
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基因ID
- 2892
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UniProt
- P42263
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途径
- PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane
抗原
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