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Glutamate Receptor 3 抗体 (AA 451-550)

This anti-Glutamate Receptor 3 antibody is a 兔 多克隆 antibody detecting Glutamate Receptor 3 in ELISA, FACS, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人 和 大鼠.
产品编号 ABIN734603
发货至: 中国

Quick Overview for Glutamate Receptor 3 抗体 (AA 451-550) (ABIN734603)

抗原

See all Glutamate Receptor 3 (GRIA3) 抗体
Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

适用

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人, 大鼠

宿主

  • 58
  • 9
  • 1

克隆类型

  • 60
  • 8
多克隆

标记

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This Glutamate Receptor 3 antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 10
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    • 1
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    • 1
    • 1
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    • 1
    AA 451-550

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GLUR3

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

    别名

    GLUR3/GRIA 3

    背景

    Synonyms: GLUR3, GLURC, GluA3, MRX94, GLUR-C, GLUR-K3, Glutamate receptor 3, GluR-3, AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, GRIA3

    Background: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

    基因ID

    2892

    UniProt

    P42263

    途径

    PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane
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