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GRIA2 抗体 (AA 151-250)

This 兔 多克隆 anti-GRIA2 antibody specifically detects GRIA2 in WB, ELISA, IF (p), IF (cc), IHC (p), FACS 和 IHC (fro). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN734588
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GRIA2 抗体 (AA 151-250) (ABIN734588)

抗原

See all GRIA2 抗体
GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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  • 41
多克隆

标记

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This GRIA2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 151-250

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GLUR2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

    别名

    GLUR2

    背景

    Synonyms: GLUR2, GLURB, GluA2, HBGR2, GluR-K2, Glutamate receptor 2, GluR-2, AMPA-selective glutamate receptor 2, GluR-B, Glutamate receptor ionotropic, AMPA 2, GRIA2

    Background: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

    基因ID

    2891

    UniProt

    P42262

    途径

    PI3K-Akt Signaling
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