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DPYSL2 抗体 (AA 1-100)

This anti-DPYSL2 antibody is a 兔 多克隆 antibody detecting DPYSL2 in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN734468
发货至: 中国

Quick Overview for DPYSL2 抗体 (AA 1-100) (ABIN734468)

抗原

See all DPYSL2 抗体
DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

适用

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人, 小鼠, 大鼠

宿主

  • 120
  • 3

克隆类型

  • 114
  • 9
多克隆

标记

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This DPYSL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 38
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    AA 1-100

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CRMP2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Tang, Li, Su, Fu, Zou, Wang, Li: "Absence of miR-223-3p ameliorates hypoxia-induced injury through repressing cardiomyocyte apoptosis and oxidative stress by targeting KLF15." in: European journal of pharmacology, Vol. 841, pp. 67-74, (2019) (PubMed).

    Zheng, Liu, Li, Tang, Zhang, Tang: "Lithium posttreatment confers neuroprotection through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats." in: Journal of neurosurgery, pp. 1-9, (2016) (PubMed).

  • 抗原

    DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

    别名

    CRMP2

    背景

    Synonyms: Collapsin response mediator protein 2, Collapsin response mediator protein hCRMP 2, CRAM, CRMP 2, CRMP-2, CRMP2, DHPRP 2, DHPRP2, Dihydr pyrimidinase 2, Dihydropyrimidinase 2, Dihydropyrimidinase like 2, Dihydropyrimidinase like 2 long form, Dihydropyrimidinase related protein 2, Dihydropyrimidinase-related protein 2, DPYL 2, DPYL2, DPYL2_HUMAN, DPYSL 2, Dpysl2, DRP 2, DRP-2, DRP2, Musunc 33, Musunc33, N2A3, TOAD 64, TOAD64, ULIP 2 protein, ULIP-2, Ulip2, Unc-33-like phosphoprotein 2.

    Background: Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance. CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification. The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction. CRMPs localize to the lamellipodia and filopodia of axonal growth cones, suggesting a role in axon guidance. Moreover, CRMP2 is upregulated after axotomy, and appears to increase the formation of axon-type processes from hippocampal neurons. CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly. CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome. Interaction studies have implicated phospholipase D2 (PLD2), the cytosolic tyrosine kinase Fes, and intersectin in CRMP function. Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease.

    基因ID

    1808

    UniProt

    Q16555

    途径

    Regulation of Cell Size
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