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Cyclin H 抗体 (AA 221-323)

This anti-Cyclin H antibody is a 兔 多克隆 antibody detecting Cyclin H in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人 和 大鼠.
产品编号 ABIN734408
发货至: 中国

Quick Overview for Cyclin H 抗体 (AA 221-323) (ABIN734408)

抗原

See all Cyclin H (CCNH) 抗体
Cyclin H (CCNH)

适用

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人, 大鼠

宿主

  • 71
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克隆类型

  • 64
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多克隆

标记

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This Cyclin H antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 221-323

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Cyclin H

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Cyclin H (CCNH)

    别名

    Cyclin H

    背景

    Synonyms: CAK, p34, p37, CycH, Cyclin-H, MO15-associated protein, CCNH

    Background: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

    基因ID

    902

    UniProt

    P51946

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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