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SELPLG 抗体 (FineTest®647)

This FineTest®647-conjugated 大鼠 单克隆 anti-SELPLG antibody (Clone 4RA10) specifically detects SELPLG in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN7675465
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for SELPLG 抗体 (FineTest®647) (ABIN7675465)

抗原

See all SELPLG 抗体
SELPLG (Selectin P Ligand (SELPLG))

适用

  • 93
  • 43
  • 22
  • 1
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  • 1
小鼠

宿主

  • 78
  • 30
  • 21
  • 9
大鼠

克隆类型

  • 69
  • 64
  • 3
单克隆

标记

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This SELPLG antibody is conjugated to FineTest®647

应用范围

  • 74
  • 70
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  • 26
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  • 7
  • 2
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Flow Cytometry (FACS)

克隆位点

4RA10
  • 原理

    FineTest®647 Anti-Mouse CD162 Antibody

    亚型

    IgG1, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    SELPLG (Selectin P Ligand (SELPLG))

    别名

    CD162

    背景

    Synonyms: CD162|P-selectin glycoprotein ligand 1|PSGL-1|Selectin P ligand|Selplg|PSGL1

    Background: The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selpl gene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, Selpl mRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L.

    分子量

    0

    基因ID

    20345

    UniProt

    Q62170
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