VWF 抗体
Quick Overview for VWF 抗体 (ABIN7674597)
抗原
See all VWF 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- VWF, VWFpp antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- von Willebrand factor
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亚型
- IgG
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应用备注
- WB: 1:200-1:2000, IHC: 1:100-1:400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- VWF (Von Willebrand Factor (VWF))
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别名
- VWF
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背景
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Synonyms: von Willebrand factor (vWF)|von Willebrand antigen 2 Alternative names: von Willebrand antigen II|VWF|F8VWF
Background: Von Willebrand factor(vWF) is a large multimeric glycoprotein that is crucial to the hemostasis process. It supports platelet adhesion and carries factor VIII(FVIII). Deficiency of vWF results in von Willebrand disease(vWD), a common inherited bleeding disorder. The pre-pro-vWF is comprised of 2,813 amino acids(aa) which encompass a 22-aa signal peptide, a 741-aa large propeptide(vWF propeptide, vWFpp, also called von Willebrand antigen II) and 2,050 aa making up the mature vWF. The von Willebrand antigen 2 is required for multimerization of vWF and for its targeting to storage granules. This antibody raised against the N-terminal region of pre-pro-vWF recognizes von Willebrand antigen 2(75-83 kDa) and pro-vWF(309-320 kDa).
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分子量
- 75 kDa, 309 kDa
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UniProt
- P04275
抗原
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