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VWF 抗体

The 兔 多克隆 anti-VWF antibody is suitable to detect VWF in samples from 人, 大鼠 和 小鼠. It has been validated for IHC, WB 和 ELISA.
产品编号 ABIN7674597
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for VWF 抗体 (ABIN7674597)

抗原

See all VWF 抗体
VWF (Von Willebrand Factor (VWF))

适用

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人, 大鼠, 小鼠

宿主

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  • 110
  • 13
  • 7
  • 3
  • 2
  • 1

克隆类型

  • 147
  • 102
  • 2
多克隆

标记

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This VWF antibody is un-conjugated

应用范围

  • 145
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  • 45
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Immunohistochemistry (IHC), Western Blotting (WB), ELISA
  • 原理

    VWF, VWFpp antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    von Willebrand factor

    亚型

    IgG
  • 应用备注

    WB: 1:200-1:2000, IHC: 1:100-1:400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    VWF (Von Willebrand Factor (VWF))

    别名

    VWF

    背景

    Synonyms: von Willebrand factor (vWF)|von Willebrand antigen 2 Alternative names: von Willebrand antigen II|VWF|F8VWF

    Background: Von Willebrand factor(vWF) is a large multimeric glycoprotein that is crucial to the hemostasis process. It supports platelet adhesion and carries factor VIII(FVIII). Deficiency of vWF results in von Willebrand disease(vWD), a common inherited bleeding disorder. The pre-pro-vWF is comprised of 2,813 amino acids(aa) which encompass a 22-aa signal peptide, a 741-aa large propeptide(vWF propeptide, vWFpp, also called von Willebrand antigen II) and 2,050 aa making up the mature vWF. The von Willebrand antigen 2 is required for multimerization of vWF and for its targeting to storage granules. This antibody raised against the N-terminal region of pre-pro-vWF recognizes von Willebrand antigen 2(75-83 kDa) and pro-vWF(309-320 kDa).

    分子量

    75 kDa, 309 kDa

    UniProt

    P04275
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