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CD8 alpha 抗体 (PE-Cy5.5)

This anti-CD8 alpha antibody is a 小鼠 单克隆 antibody detecting CD8 alpha in FACS. Suitable for 人.
产品编号 ABIN7673945
发货至: 中国

Quick Overview for CD8 alpha 抗体 (PE-Cy5.5) (ABIN7673945)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD8 alpha antibody is conjugated to PE-Cy5.5

应用范围

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Flow Cytometry (FACS)

克隆位点

OKT-8
  • 原理

    PE-Cy5.5 Anti-Human CD8a Antibody

    纯化方法

    0

    纯度

    0

    亚型

    IgG2a, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8a

    背景

    Synonyms: CD8A|MAL|T-cell surface glycoprotein CD8 alpha chain|T-lymphocyte differentiation antigen T8/Leu-2

    Background: CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

    分子量

    0

    基因ID

    925

    UniProt

    P01732

    途径

    TCR Signaling
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