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2B4 抗体 (PE-Cy5)

This anti-2B4 antibody is a 小鼠 单克隆 antibody detecting 2B4 in FACS. Suitable for 人.
产品编号 ABIN7673809
发货至: 中国

Quick Overview for 2B4 抗体 (PE-Cy5) (ABIN7673809)

抗原

See all 2B4 (CD244) 抗体
2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This 2B4 antibody is conjugated to PE-Cy5

应用范围

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Flow Cytometry (FACS)

克隆位点

C1-7
  • 原理

    PE-Cy5 Anti-Human CD244 Antibody

    纯化方法

    0

    纯度

    0

    亚型

    IgG1, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

    别名

    CD244

    背景

    Synonyms: 2B4|SLAMF4

    Background: CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.

    分子量

    0

    基因ID

    51744

    UniProt

    Q9BZW8
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