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SIRPA 抗体 (PE)

This anti-SIRPA antibody is a 小鼠 单克隆 antibody detecting SIRPA in FACS. Suitable for 人.
产品编号 ABIN7673554
发货至: 中国

Quick Overview for SIRPA 抗体 (PE) (ABIN7673554)

抗原

See all SIRPA 抗体
SIRPA (Signal-Regulatory Protein alpha (SIRPA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SIRPA antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

SE5A5
  • 原理

    PE Anti-Human CD172a/b Antibody

    纯化方法

    0

    纯度

    0

    亚型

    IgG1, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    SIRPA (Signal-Regulatory Protein alpha (SIRPA))

    别名

    CD172a

    背景

    Synonyms: SIRPa|SIRPb|SIRPalpha/beta|BIT|SHPS1|MFR|P84|PTPNS1|CD172 antigen-like family member A|CD172 antigen-like family member B

    Background: CD172a, also known as signal-regulatory protein α (SIRPα), src homology 2 domain-containing phosphatase substrate-1 (SHPS1), PTPNS1, BIT, MFR, and P84, is a 75-110 kD transmembrane glycoprotein involved in receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily and is primarily expressed on monocytes/macrophages, granulocytes, dendritic cells, and neurons. CD172a serves as a substrate of activated receptor tyrosine kinases (RTKs). The interaction of CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion, and phagocytosis. CD47 (IAP) is the extracellular ligand for CD172a. SIRPα was recently demonstrated to be a specifc marker for cardiomyocytes derived from human pluripotent stem cells2.

    分子量

    0

    基因ID

    140885

    UniProt

    O00241
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