MTDH 抗体
Quick Overview for MTDH 抗体 (ABIN7673471)
抗原
See all MTDH 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MTDH-Specific antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- metadherin
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- MTDH (Metadherin (MTDH))
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别名
- MTDH
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背景
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Synonyms: Protein LYRIC|3D3/LYRIC|Astrocyte elevated gene-1 protein (AEG-1)|Lysine-rich CEACAM1 co-isolated protein|Metadherin|Metastasis adhesion protein|MTDH|AEG1|LYRIC
Background: MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22, the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma, and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH.
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分子量
- 64 kDa
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基因ID
- 92140
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UniProt
- Q86UE4
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途径
- Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
抗原
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