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Cytokeratin 1 抗体

This anti-Cytokeratin 1 antibody is a 兔 多克隆 antibody detecting Cytokeratin 1 in WB, IHC, ELISA, IP 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN7673427
发货至: 中国

Quick Overview for Cytokeratin 1 抗体 (ABIN7673427)

抗原

See all Cytokeratin 1 (KRT1) 抗体
Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

适用

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人, 小鼠

宿主

  • 76
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  • 1

克隆类型

  • 69
  • 56
多克隆

标记

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This Cytokeratin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
  • 原理

    KRT1-specific antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: Peptide

    Immunogen: keratin 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

    别名

    KRT1

    背景

    Synonyms: Keratin, type II cytoskeletal 1|67 kDa cytokeratin|Cytokeratin-1 (CK-1)|Hair alpha protein|Keratin-1 (K1)|Type-II keratin Kb1|KRT1|KRTA

    Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9-K23, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins, Hb1-Hb6. Keratin-1 is type II keratin. It is a specific marker for terminal differentiation in mammalian epidermis. It is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. This antibody is specifically against ketatin I.

    分子量

    67 kDa

    UniProt

    P04264
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