Fc epsilon RI/FCER1A 抗体 (FITC)
Quick Overview for Fc epsilon RI/FCER1A 抗体 (FITC) (ABIN7673258)
抗原
See all Fc epsilon RI/FCER1A (FCER1A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- FITC Anti-Mouse FcεRIα Antibody
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纯化方法
- 0
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纯度
- 0
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亚型
- IgG
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应用备注
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- 4 °C
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储存方法
- 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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别名
- FcepsilonRIalpha
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背景
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Synonyms: Fc-epsilon RI-alpha|FcERI|Fcer1a|High affinity immunoglobulin epsilon receptor subunit alpha
Background: FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.
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分子量
- 0
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基因ID
- 14125
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UniProt
- P20489
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途径
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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