CD47 抗体 (FITC)
Quick Overview for CD47 抗体 (FITC) (ABIN7673142)
抗原
See all CD47 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- FITC Anti-Human CD47 Antibody
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纯化方法
- 0
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纯度
- 0
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亚型
- IgG1, kappa
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应用备注
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- 4 °C
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储存方法
- 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- CD47
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别名
- CD47
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背景
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Synonyms: IAP|Rh-associated protein|gp42|integrin-associated protein|neurophilin
Background: CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47, in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
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分子量
- 0
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基因ID
- 961
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UniProt
- Q08722
抗原
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