ST5 抗体
Quick Overview for ST5 抗体 (ABIN7673013)
抗原
See all ST5 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DENND2B antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- suppression of tumorigenicity 5
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- ST5 (Suppression of Tumorigenicity 5 (ST5))
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别名
- DENND2B
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背景
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Synonyms: DENN domain-containing protein 2B|HeLa tumor suppression 1|Suppression of tumorigenicity 5 protein|DENND2B|HTS1|ST5
Background: Guanine nucleotide exchange factor(GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.
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分子量
- 150 kDa
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基因ID
- 6764
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UniProt
- P78524
抗原
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