Acetyl-CoA Carboxylase alpha 抗体 (AA 2223-2346)
Quick Overview for Acetyl-CoA Carboxylase alpha 抗体 (AA 2223-2346) (ABIN7672612)
抗原
See all Acetyl-CoA Carboxylase alpha (ACACA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 2223-2346
-
原理
- ACC1 antibody
-
纯化方法
- Protein A+G purification
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
-
Immunogen sequence: 2223-2346aa
Immunogen: acetyl-Coenzyme A carboxylase alpha
-
亚型
- IgG2a
-
-
-
-
应用备注
- WB: 1:2000-1:10000, IHC: 1:100-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
有效期
- 12 months
-
-
- Acetyl-CoA Carboxylase alpha (ACACA)
-
别名
- ACC1
-
背景
-
Synonyms: Acetyl-CoA carboxylase 1 (ACC1)|Acetyl-Coenzyme A carboxylase alpha (ACC-alpha)|ACACA|ACAC|ACC1|ACCA
Background: ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.
-
分子量
- 270 kDa
-
基因ID
- 31
-
UniProt
- Q13085
-
途径
- AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect
抗原
-