VCAM1 抗体
Quick Overview for VCAM1 抗体 (ABIN7670763)
抗原
See all VCAM1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- VCAM-1/CD106 Polyclonal Antibody(Capture/Detector)
-
纯化方法
- Antigen Affinity Purification
-
免疫原
- Recombinant Rat VCAM-1/CD106 protein expressed by Mammalian
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:1000,IHC 1:1000-1:2000,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- Sterile PBS , pH 7.4
-
储存液
- Without preservative
-
注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
-
有效期
- 12 months
-
-
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
-
别名
- VCAM-1/CD106
-
背景
- CD106,Vcam1,Vcam-1,V-CAM 1,VascuLar ceLL adhesion protein 1,SoLubLe VascuLar CeLL Adhesion MoLecuLe-1,Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses,binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation.
-
分子量
-
Calculated MW: 81kDa
ObservedMW: 75-100kDa
-
UniProt
- P29534
-
途径
- Carbohydrate Homeostasis
抗原
-