SNCA 抗体
Our Local Distributor
北京 101111
Quick Overview for SNCA 抗体 (ABIN7670750)
抗原
See all SNCA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- alpha-Synuclein/SNCA Monoclonal Antibody(Capture)
-
纯化方法
- Protein A/G Purification
-
免疫原
- Recombinant Human alpha-Synuclein/SNCA protein expressed by E.coli
-
亚型
- IgM
-
-
-
-
应用备注
- ELISA Capture 2-8 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- Sterile PBS , pH 7.4
-
储存液
- Without preservative
-
注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
-
有效期
- 12 months
-
-
- SNCA (Synuclein, alpha (SNCA))
-
别名
- alpha-Synuclein/SNCA
-
背景
- SNC-A,aSYN,PD1,NACP,PARK1,PARK4,Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
-
UniProt
- P37840
-
途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
-