PTX3 抗体
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北京 101111
Quick Overview for PTX3 抗体 (ABIN7670715)
抗原
See all PTX3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Pentraxin 3/TSG-14 Polyclonal Antibody(Capture/Detector)
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Rat Pentraxin 3/TSG-14 protein expressed by E.coli
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亚型
- IgG
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anti-Pentraxin 3 (PTX3) (AA 282-380) antibody
PTX3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-Pentraxin 3 (PTX3) (AA 151-250) antibodyPTX3 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pentraxin 3 (PTX3) (AA 99-164) antibodyPTX3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pentraxin 3 (PTX3) (AA 282-380) antibodyPTX3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-Pentraxin 3 (PTX3) (N-Term) antibodyPTX3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Pentraxin 3 (PTX3) (N-Term) antibodyPTX3 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pentraxin 3 (PTX3) (AA 183-381) antibodyPTX3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pentraxin 3 (PTX3) (N-Term) antibodyPTX3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pentraxin 3 (PTX3) (AA 183-381) antibodyPTX3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pentraxin 3 (PTX3) (AA 18-240) antibodyPTX3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- PTX3 (Pentraxin 3 (PTX3))
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别名
- Pentraxin 3/TSG-14
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背景
- Ptx3,Ptx-3,Pentraxin 3,Pentraxin 3 (PTX3),TSG-14,was initially identified as a TNF-alpha or Il-1 beta inducible gene. It belongs to the pentraxin family,which was named originally for the homo-pentameric structure formed by its members. The pentraxin family is divided into two subfamilies: the ""short"" and the ""long"" pentraxins with approximate molecular weights of 25 kDa and 50 kDa,respectively. TSG-14 is a member of the long pentraxin subfamily,which also includes the Xenopus laevis Xl-PXN1,the guinea pig apexin/p50,the rat neuronal pentraxin I (NPI) and NPR,the human neuronal pentraxin II (NPTX2) and the human neuronal activity-related pentraxin.Mature secreted TSG-14 contains a pentaxin-like domain at its carboxy-terminus that shares 23?28 % amino acid (aa) sequence similarity to C-reactive protein (CRP) and serum amyloid P component (SAP),which belongs to the short pentraxin subfamily. However,the N-terminal sequence of TSG-14 does not share aa sequence homology with any of the ""short"" pentaxins. Unlike CRP and SAP,which forms pentamers only,TSG-14 forms both pentameric and higher ordered oligomers. Similarly to CRP and SAP,TSG-14 binds to the complement cascade component C1q. However,TSG-14 does not bind to phosphoethanolamine,phosphocholine,or high pyruvate agarose,which are known ligands for CRP and SAP. TSG-14 is a marker of the acute phase response and is highly expressed in advanced atherosclerotic plaques. While CRP and SAP are primarily produced in the liver,TSG-14 expression is strongly up?regulated by TNF-alpha,Il-1 beta,and bacterial lPS in peripheral fibroblasts,endothelial cells,and macrophages.
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UniProt
- D3ZT94
抗原
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