OxLDL 抗体
This anti-OxLDL antibody is a 小鼠 单克隆 antibody detecting OxLDL in ELISA (Detection). Suitable for 人.
Quick Overview for OxLDL 抗体 (ABIN7670708)
抗原
See all OxLDL 抗体
OxLDL
(Oxidized Low Density Lipoprotein (OxLDL))
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This OxLDL antibody is un-conjugated
应用范围
ELISA (Detection)
克隆位点
15F5
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原理
- OxLDL Monoclonal Antibody(Detector)
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纯化方法
- Protein A/G Purification
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免疫原
- Human OxLDL Native Protein
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亚型
- IgG1
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anti-Oxidized Low Density Lipoprotein (OxLDL) antibody
OxLDL 适用: 小鼠, 人 IF (p), FACS, IF (cc), IHC (p), ELISA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- OxLDL (Oxidized Low Density Lipoprotein (OxLDL))
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别名
- OxLDL
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背景
- Oxidized LDL,Ox LDL,Ox-LDL,Oxidized lDl (Ox-lDl) is a class of modified lDl. In addition to oxidation-modified lDl,modified lDl also includes acetylated lDl directly combined with malondialdehyde (MDA) and 4-hydroxylenic acid (4-HNE). These lDl which are not oxidation-modified but only chemically modified are called derived lDl. Different from derived lDl,Ox-lDl has unique physiological characteristics in the following aspects: (1) Ox-lDl can affect the metabolism of arachidonic acid and inhibit the esterification of cholesterol,but the derived lDl has no such effect,(2) Ox-lDl consumes endogenous antioxidant substances in lDl and reduces vitamin E content in lDl,while MDA-lDl has no such effect,(3) Oxidative modification involves lipid peroxidation,and PUFAs in lDl are oxidized,(4) When oxidized lDl is low in oxidation degree,ApoB degrades,When the oxidation degree is high,ApoB can be repolymerized. Ox-lDl is not metabolized by lDl receptors,and is recognized,bound,and endocytosed into cells by scavorator receptors. The normal cholesterol metabolism pathway is lost,resulting in intracellular lipid deposition and foam-like transformation.
抗原
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