Neuropilin 1 抗体
Quick Overview for Neuropilin 1 抗体 (ABIN7670696)
抗原
See all Neuropilin 1 (NRP1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Neuropilin-1 Polyclonal Antibody(Capture/Detector)
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Human Neuropilin-1 protein expressed by Mammalian
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亚型
- IgG
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anti-Neuropilin 1 (NRP1) (AA 646-814) antibody
NRP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) (AA 646-814) antibodyNRP1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Neuropilin 1 (NRP1) (AA 22-131) antibodyNRP1 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Neuropilin 1 (NRP1) (AA 21-250) antibodyNRP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) antibodyNRP1 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) (AA 722-750) antibodyNRP1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) (AA 45-59) antibodyNRP1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5B1E11 unconjugated
anti-Neuropilin 1 (NRP1) (AA 722-750), (C-Term) antibodyNRP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22995 unconjugated
anti-Neuropilin 1 (NRP1) (AA 502-514), (Extracellular) antibodyNRP1 适用: 人 WB, FACS, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 1 (NRP1) (AA 851-923) antibodyNRP1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- Neuropilin 1 (NRP1)
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别名
- Neuropilin-1
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背景
- Neuropilin-1,Vascular endothelial cell growth factor 165 receptor,CD304,NRP1,NRP,VEGF165R,Neuropilin-1 (Npn-1, previously neuropilin, also CD304) is a 130 - 140 kDa type I transmembrane (TM) glycoprotein that regulates axon guidance and angiogenesis. Two homologues, Neuropilin-1 and Neuropilin-2, are identified. Neuropilin-1 binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. NRP1 expression is regulated in EC by tumor necrosis factor-alpha, the transcription factors dHAND and Ets-1, and vascular injury. NRP1 upregulation is positively correlated with the progression of various tumors.
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UniProt
- O14786
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途径
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
抗原
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