Lipocalin 2 抗体
Quick Overview for Lipocalin 2 抗体 (ABIN7670681)
抗原
See all Lipocalin 2 (LCN2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Lipocalin-2/NGAL Polyclonal Antibody(Capture/Detector)
-
纯化方法
- Antigen Affinity Purification
-
免疫原
- Recombinant Human Lipocalin-2/NGAL protein expressed by E.coli
-
亚型
- IgG
-
-
anti-Lipocalin 2 (LCN2) (AA 21-200) antibody
LCN2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-200) antibodyLCN2 适用: 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 101-198) antibodyLCN2 适用: 人 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 1-100) antibodyLCN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 大鼠 WB, IHC 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Lipocalin 2 (LCN2) (AA 1-198) antibodyLCN2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) antibodyLCN2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1A1B2 unconjugated
-
-
应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- Sterile PBS , pH 7.4
-
储存液
- Without preservative
-
注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
-
有效期
- 12 months
-
-
- Lipocalin 2 (LCN2)
-
别名
- Lipocalin-2/NGAL
-
背景
- LCN2,HNL,NGAL,NeutrophiL geLatinase-associated LipocaLin,25 kDa aLpha-2-microgLobuLin-reLated subunit of MMP-9,LipocaLin-2,Oncogene 24p3,SiderocaLin,p25,Iron-trafficking protein involved in multiple processes such as apoptosis,innate immunity and renal development.Binds iron through association with 2,3-dihydroxybenzoic acid (2,3-DHBA),a siderophore that shares structural similarities with bacterial enterobactin,and delivers or removes iron from the cell,depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SlC22A17 (24p3R) receptor,leading to release of iron and subsequent increase of intracellular iron concentration. In contrast,association of the iron-free form (apo-24p3) with the SlC22A17 (24p3R) receptor is followed by association with an intracellular siderophore,iron chelation and iron transfer to the extracellular medium,thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (Il3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis,while iron-free form decreases intracellular iron levels,inducing expression of the proapoptotic protein BCl2l11/BIM,resulting in apoptosis.Involved in innate immunity,limits bacterial proliferation by sequestering iron bound to microbial siderophores,such as enterobactin.Can also bind siderophores from M.tuberculosis.
-
UniProt
- P80188
-
途径
- Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
抗原
-
