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IL32 抗体

This anti-IL32 antibody is a 大鼠 单克隆 antibody detecting IL32 in ELISA (Detection). Suitable for 人.
产品编号 ABIN7670668
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL32 抗体 (ABIN7670668)

抗原

See all IL32 抗体
IL32 (Interleukin 32 (IL32))

适用

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宿主

  • 49
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大鼠

克隆类型

  • 51
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单克隆

标记

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This IL32 antibody is un-conjugated

应用范围

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ELISA (Detection)

克隆位点

4D9
  • 原理

    IL-32 Monoclonal Antibody(Detector)

    纯化方法

    Protein A/G Purification

    免疫原

    Recombinant Human IL-32 protein expressed by E.coli

    亚型

    IgG1
  • 应用备注

    ELISA Detector 0.1-0.4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Sterile PBS , pH 7.4

    储存液

    Without preservative

    注意事项

    Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C Valid for 1 month or -20°C Valid for 12 months

    有效期

    12 months
  • 抗原

    IL32 (Interleukin 32 (IL32))

    别名

    IL-32

    背景

    Interleukin-32,IL-32,Natural killer cells protein 4,Tumor necrosis factor alpha-inducing factor,IL32,NK4,TAIF,IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, Mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis, and in the human stomach cancer, human lung cancer, and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer.

    UniProt

    P24001
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