IL32 抗体
Our Local Distributor
北京 101111
Quick Overview for IL32 抗体 (ABIN7670667)
抗原
See all IL32 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- IL-32 Polyclonal Antibody(Capture)
-
纯化方法
- Antigen Affinity Purification
-
免疫原
- Recombinant Human IL-32 protein expressed by E.coli
-
亚型
- IgG
-
-
-
-
应用备注
- ELISA Capture 2-8 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- Sterile PBS , pH 7.4
-
储存液
- Without preservative
-
注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
-
有效期
- 12 months
-
-
- IL32 (Interleukin 32 (IL32))
-
别名
- IL-32
-
背景
- Interleukin-32,IL-32,Natural killer cells protein 4,Tumor necrosis factor alpha-inducing factor,IL32,NK4,TAIF,IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, Mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis, and in the human stomach cancer, human lung cancer, and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer.
-
UniProt
- P24001
抗原
-