Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C Valid for 1 month or -20°C Valid for 12 months
有效期
12 months
抗原
IL29
(Interleukin 29 (IL29))
别名
IL-29/IFN-lambda1
背景
InterLeukin-29(IL-29),IFNL1,ZCYTO21,Interferon Lambda-1,IFN-Lambda-1,Cytokine Zcyto21,IL29,Cytokine with antiviral,antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense,predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of Il10RB and IFNlR1,and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG),which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNlR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.