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IL-22 抗体

This 小鼠 单克隆 anti-IL-22 antibody (Clone 8H8) specifically detects IL-22 in ELISA (Capture). The antibody is reactive with 人 samples.
产品编号 ABIN7670664
发货至: 中国
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Quick Overview for IL-22 抗体 (ABIN7670664)

抗原

See all IL-22 (IL22) 抗体
IL-22 (IL22) (Interleukin 22 (IL22))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-22 antibody is un-conjugated

应用范围

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ELISA (Capture)

克隆位点

8H8
  • 原理

    IL-22 Monoclonal Antibody(Capture)

    纯化方法

    Protein A/G Purification

    免疫原

    Recombinant Human IL-22 protein expressed by Mammalian

    亚型

    IgG1
  • 应用备注

    ELISA Capture 2-8 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Sterile PBS , pH 7.4

    储存液

    Without preservative

    注意事项

    Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C Valid for 1 month or -20°C Valid for 12 months

    有效期

    12 months
  • 抗原

    IL-22 (IL22) (Interleukin 22 (IL22))

    别名

    IL-22

    背景

    Cytokine Zcyto18,IL-10-reLated T-ceLL-derived inducibLe factor,IL22,IL-22,IL-D110,IL-TIF,ILTIFIL-10-reLated T-ceLL-derived-inducibLe factor,IL-TIFMGC79382,interLeukin 22,interLeukin-22,MGC79384,TIFa,TIFIL-23,zcyto18,Interleukin-22 (Il-22),also known as Il-10-related T cell-derived inducible factor (Il-TIF) was initially identified as a gene induced by Il-9 in mouse T cells and mast cells. Mouse Il-22 cDNA encodes a 179 amino acid (aa) residue protein with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79 % and 22 % aa sequence identity with human Il-22 and Il-10,respectively. The mouse Il-22 gene is localized to chromosome 10. Although it exists as a single copy gene in many mouse strains,the Il-22 gene is duplicated in some mouse strains including C57B1/6,FVB and 129. The two mouse genes designated Il-TIF alpha and Il-TIF beta,share greater than 98 % sequence homology in their coding region. Il-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. Il-22 is produced by normal mouse T cells upon Con A activation. Mouse Il-22 expression is also induced in various organs upon lipopolysaccharide injection,suggesting that Il-22 may be involved in inflammatory responses. The functional Il-22 receptor complex consists of two receptor subunits,Il-22 R (previously an orphan receptor named CRF2-9) and Il-10 R beta (previously known as CRF2-4),belonging to the class II cytokine receptor family.

    UniProt

    Q9GZX6
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