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IFNA1 抗体

The 大鼠 单克隆 anti-IFNA1 antibody (Clone 9B3) (ABIN7670653) specifically detects IFNA1 in ELISA (Detection). The antibody is reactive with 小鼠 samples.
产品编号 ABIN7670653
发货至: 中国
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Quick Overview for IFNA1 抗体 (ABIN7670653)

抗原

See all IFNA1 抗体
IFNA1 (Interferon, alpha 1 (IFNA1))

适用

  • 75
  • 14
  • 3
  • 2
  • 2
小鼠

宿主

  • 42
  • 36
  • 3
大鼠

克隆类型

  • 44
  • 37
单克隆

标记

  • 38
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This IFNA1 antibody is un-conjugated

应用范围

  • 33
  • 23
  • 15
  • 13
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA (Detection)

克隆位点

9B3
  • 原理

    IFN-alpha 1 Monoclonal Antibody(Detector)

    纯化方法

    Protein A/G Purification

    免疫原

    Recombinant Mouse IFN-alpha 1 protein expressed by Mammalian

    亚型

    IgM
  • 应用备注

    ELISA Detector 0.1-0.4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Sterile PBS , pH 7.4

    储存液

    Without preservative

    注意事项

    Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C Valid for 1 month or -20°C Valid for 12 months

    有效期

    12 months
  • 抗原

    IFNA1 (Interferon, alpha 1 (IFNA1))

    别名

    IFN-alpha 1

    背景

    Ifna,IL-1ra Homolog,IFN-α,IL-1F,IL-1L,IL-1HY,IL-1RP,IFN-alpha,FIL1 delta,IFN-alpha-1,IFN-α1,IL-1 delta,IL-1F5,IL-1HY1,IL-1L1,IL-1ra Homolog 1,IL-1RP3,Ifna1,The interferons (IFN) are a family of cytokines with potent antiviral, antiproliferative and immunomodulatory properties, and classified based on their binding specificity to cell surface receptors. The type I IFN bind to the interferon alpha receptor (IFNAR), which consists of two subunits: IFNAR1 ( alpha -subunit) and IFNAR2 ( beta -subunit). This binding contributes to TNF-alpha induced signaling. Both the human and mouse genome code for more than a dozen closely related IFNa subtypes and the varous IFN a share about 80 % sequence homology among them. Interferon-alpha 1 (IFNA1) is a secreted, approximately 19 kDa member of the type I interferon family of molecules. Mature mouse IFN-alpha 1 shares 63 % and 82 % amino acid sequence identity with human and rat IFN-alpha 1, respectively. Low level IFN-alpha is detected under physiological conditions, and the production of IFNs is markedly enhanced during virus infection. Although originally discovered by its capability to fight virus replication, IFN-alpha functions as a prototypic tumor suppressor that represses the clinical tumorigenic phenotype in some malignancies.

    UniProt

    P01572

    途径

    JAK/STAT Signaling, Hepatitis C
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