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Frataxin 抗体

This anti-Frataxin antibody is a 兔 多克隆 antibody detecting Frataxin in ELISA. Suitable for 人.
产品编号 ABIN7670612
发货至: 中国

Quick Overview for Frataxin 抗体 (ABIN7670612)

抗原

See all Frataxin (FXN) 抗体
Frataxin (FXN)

适用

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宿主

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克隆类型

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多克隆

标记

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This Frataxin antibody is un-conjugated

应用范围

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ELISA
  • 原理

    Frataxin/FXN Polyclonal Antibody

    纯化方法

    Antigen Affinity Purification

    免疫原

    Recombinant Human Frataxin/FXN protein expressed by E.coli

    亚型

    IgG
  • 应用备注

    ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Sterile PBS , pH 7.4

    储存液

    Without preservative

    注意事项

    Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C Valid for 1 month or -20°C Valid for 12 months

    有效期

    12 months
  • 抗原

    Frataxin (FXN)

    别名

    Frataxin/FXN

    背景

    CyaY,d-FXN,FA,FARR,Frataxin mature form,Frataxin(81-210),FRDA,FRDA,Friedreich ataxia protein,Fxn,i-FXN,m56-FXN,m78-FXN,m81-FXN,MGC57199,X25,FXN,also named as FRDA,X25,m81-FXN,d-FXN,m78-FXN and i-FXN,belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. FXN is expressed in the cytoplasm as a 210 amino acid (AA) precursor protein (pFXN, 23?KDa) that is translocated into mitochondria where it is processed by two consecutive steps into iFXN (FXN 42-210, 19?KDa) and finally mFXN (81-210, 14.2?KDa),which is functional.

    UniProt

    Q16595

    途径

    Transition Metal Ion Homeostasis, Regulation of Cell Size
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