Frataxin 抗体
Quick Overview for Frataxin 抗体 (ABIN7670612)
抗原
See all Frataxin (FXN) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Frataxin/FXN Polyclonal Antibody
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Human Frataxin/FXN protein expressed by E.coli
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亚型
- IgG
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应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- Frataxin (FXN)
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别名
- Frataxin/FXN
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背景
- CyaY,d-FXN,FA,FARR,Frataxin mature form,Frataxin(81-210),FRDA,FRDA,Friedreich ataxia protein,Fxn,i-FXN,m56-FXN,m78-FXN,m81-FXN,MGC57199,X25,FXN,also named as FRDA,X25,m81-FXN,d-FXN,m78-FXN and i-FXN,belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. FXN is expressed in the cytoplasm as a 210 amino acid (AA) precursor protein (pFXN, 23?KDa) that is translocated into mitochondria where it is processed by two consecutive steps into iFXN (FXN 42-210, 19?KDa) and finally mFXN (81-210, 14.2?KDa),which is functional.
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UniProt
- Q16595
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途径
- Transition Metal Ion Homeostasis, Regulation of Cell Size
抗原
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