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DPP4 抗体

This anti-DPP4 antibody is a 兔 多克隆 antibody detecting DPP4 in ELISA. Suitable for 人.
产品编号 ABIN7670590
发货至: 中国

Quick Overview for DPP4 抗体 (ABIN7670590)

抗原

See all DPP4 抗体
DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

适用

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宿主

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克隆类型

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多克隆

标记

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This DPP4 antibody is un-conjugated

应用范围

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ELISA
  • 原理

    DPPIV/CD26 Polyclonal Antibody(Capture/Detector)

    纯化方法

    Antigen Affinity Purification

    免疫原

    Recombinant Human DPPIV/CD26 protein expressed by Mammalian

    亚型

    IgG
  • 应用备注

    ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Sterile PBS , pH 7.4

    储存液

    Without preservative

    注意事项

    Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C Valid for 1 month or -20°C Valid for 12 months

    有效期

    12 months
  • 抗原

    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

    别名

    DPPIV/CD26

    背景

    Dipeptidyl peptidase 4,ADABP,Adenosine deaminase complexing protein 2 (ADCP-2),Dipeptidyl peptidase IV (DPP IV),T-cell activation antigen CD26,TP103,CD26,DPP4,ADCP2,CD26,CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. CD26 is expressed specifically in lymphatic vessels but not in blood vessels in the skin, small intestine, esophagus, ovary, breast and prostate glands. It acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It's binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. It may be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, it enhanced cell proliferation, a process inhibited by GPC3. It acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones.

    UniProt

    P27487

    途径

    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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