CCL21 抗体
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北京 101111
Quick Overview for CCL21 抗体 (ABIN7670566)
抗原
See all CCL21 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CCL21/6Ckine Polyclonal Antibody(Capture/Detector)
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Mouse CCL21/6Ckine protein expressed by E.coli
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亚型
- IgG
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应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
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别名
- CCL21/6Ckine
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背景
- TCA,Scya,Beta-Chemokine Exodus,Thymus-Derived Chemotactic Agent,6Ckine,Beta-Chemokine Exodus-2,C-C Motif Chemokine 21a,Small-Inducible Cytokine A21a,TCA4,Thymus-Derived Chemotactic Agent 4,Scya21,Scya21a,Ccl21a,C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CCchemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signalpeptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms whileCCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 andCXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro forthymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 showspreferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes tosecondary lymphoid organs.
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UniProt
- P84444
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途径
- Regulation of Actin Filament Polymerization
抗原
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