alpha Fetoprotein 抗体
Quick Overview for alpha Fetoprotein 抗体 (ABIN7670526)
抗原
See all alpha Fetoprotein (AFP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- alpha-Fetoprotein/AFP Monoclonal Antibody(Capture)
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纯化方法
- Protein A/G Purification
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免疫原
- Human AFP Native Protein
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亚型
- IgG1
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应用备注
- ELISA Capture 2-8 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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别名
- alpha-Fetoprotein/AFP
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背景
- ALpha-fetoprotein,ALpha-1-fetoprotein,ALpha-fetogLobuLin,AFP,HPAFP,alpha-Fetoprotein (AFP),is albuminoid superfamily protein that is synthesized in the fetus primarily by the liver,yolk sac,and tissues of gastrointestinal origin. It is one of the earliest markers of the hepatocyte lineage. AFP acts as a carrier protein for steroids,bilirubin,fatty acids,retinoids,and flavonoids. In addition,it can exert immunosuppressive activity,regulate cell proliferation and apoptosis,initiate intracellular signaling,and contribute to cell invasion. Altered levels of both fetal and maternal AFP have been associated with hypothyroidism,autoimmune disorders,and heart defects. low maternal serum AFP levels are associated with a higher incidence of Down syndrome,whereas higher levels are associated with spina bifida and anencephaly. Elevated AFP levels are also coincident with liver,stomach,and germ cell cancers.
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UniProt
- P02771
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途径
- C21-Steroid Hormone Metabolic Process
抗原
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